Blood lipoproteins

Estimation of lipoproteins using capillary blood.

Umbilical cord blood lipoproteins. Isolation and characterization of high density lipoproteins.

High density lipoproteins (d = 1.063 to 1.21 g/ml) were isolated from both individual and pooled umbilical cord blood plasma by sequential preparative ultracentrifugation. Mean total HDL concentration was 139 ± 9.1 mg/dl, with mean values for cholesterol and triglyceride of 24.9 mg/dl and 5.0 mg/dl, respectively. The particle size distribution of HDL particles was examined by gradient gel elect...

Neonatal umbilical cord blood lipoproteins. Isolation and characterization of intermediate density and low density lipoproteins.

Intermediate density lipoproteins (IDL) (d = 1.006 to 1.019 g/ml) and low density lipoproteins (LDL) (d = 1.019 to 1.063 g/ml) were isolated from human umbilical cord blood plasma by sequential ultracentrifugation. The concentration, chemical and apolipoprotein composition, size and size distribution of the neonatal IDL and LDL for both sexes were determined. The IDL and LDL from the neonates s...

Genetic factors affecting blood lipoproteins: the candidate gene approach.

Family studies have revealed that individual variations in the levels and structures of lipoproteins in the blood are due in large part to hereditary influences. Since such lipoprotein variations are strongly associated with atherosclerosis, the major cause of heart disease and stroke, the characterization of these hereditary influences provides an opportunity to better understand the genetic c...

Biological variation of lipids and lipoproteins in fingerstick blood.

The biological variability of total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and calculated low-density lipoprotein cholesterol (LDL-C) was determined in three serial (monthly) capillary and venous specimens from 83 subjects. The analytes were quantified with a desktop analyzer. We saw no differences in the coefficient of biological variability (CVb) b...